• Users Online: 39
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2018  |  Volume : 34  |  Issue : 1  |  Page : 60-67

Assessment of audiovestibular system in patients with vitiligo: a case–control study


1 Lecturer of Audiovestibular Medicine, Ear ,Nose, Throat Department, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt
2 Lecturer of Dermatology, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt
3 Assisstant Lecturer of Dermatology Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt
4 Assistant Lecturer of Public Health, Department of Public Health and Community Medicine, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt

Correspondence Address:
Rabab Ahmed Koura
Lecturer of Audiovestibular Medicine, Ear, Nose, Throat Department, Faculty of Medicine, Beni Suef University, Yousef el Sabaee Street, 1st Settlement, New Cairo
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ejo.ejo_77_17

Rights and Permissions

Background Vitiligo is characterized by loss of epidermal melanocytes. Alterations in melanocytes in extracutaneous sites have been reported in vitiligo and sometimes implied for the inner ear along with an associated compromise in function. Aim The aim of this study was to map the auditory and vestibular functions in patients with vitiligo. Materials and methods A total of 30 patients with vitiligo vulgaris and 30 age-matched and sex-matched healthy controls were enrolled in this study. Pure tone audiometry and measurements of auditory brainstem responses, cervical vestibular-evoked myogenic potential (cVEMP), and videonystagmography (VNG) were carried out in all participants. Results Mean hearing thresholds of patients with vitiligo were highly statistically significantly lowered at 4 and 8 kHz than the controls. Analysis of brainstem auditory-evoked potentials (BAEP) revealed statistically significantly prolonged wave III, wave V, and interpeaks of I–III and I–V latencies in both ears of 18 (60%) patients and in the left ear of two (6.6%) patients in the vitiligo group than the controls. VNG findings showed canal paresis in nine (30%) patients. There was a negative statistically significant correlation between disease duration and pure tone audiometry, BAEP, and latency of N23 of cVEMP. Conclusion This study sheds light on the importance of melanocytes for proper functioning of the auditory and vestibular system. The presence of high-frequency hearing loss, BAEP abnormalities, and cVEMP changes are valuable findings in patients with vitiligo. This highlights the importance of follow-up along the disease course for early detection of auditory abnormality. cVEMP testing can be used for the evaluation of the vestibulocolic reflex in patients with vitiligo. Moreover, VNG testing can be an important tool for assessment of the vestibular system in patients with vitiligo.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed190    
    Printed4    
    Emailed0    
    PDF Downloaded34    
    Comments [Add]    

Recommend this journal