The Egyptian Journal of Otolaryngology

: 2019  |  Volume : 35  |  Issue : 2  |  Page : 135--139

Selenium supplement for treatment of geriatric rhinitis

Esin Yalcinkaya1, Hasmet Yazici2, Hakan Kayir3, Fatih K Soy2, Hesham Negm4 
1 Otolaryngology Department Koru Hospitals, Otorhinolaryngology Clinic, Ankara, Turkey
2 Otolaryngology Department, Mardin State Hospital, Ministry of Health, Otorhinolaryngology Clinic, Mardin, Turkey
3 Department of Pharmacology, Yuksek Ihtisas University, Ankara, Turkey
4 Department of Otorhinolaryngology, Faculty of Medicine, Cairo University, Cairo, Egypt

Correspondence Address:
Esin Yalcinkaya
Medicana International Hospital, Otorhinolaryngology Clinic, Ankara

With the aging of population, the incidence of geriatric problems is increasing. However, the diagnosis and treatment of geriatric problems are usually ignored. This study investigated the efficacy of supplemental selenium in patients with geriatric rhinitis (GR). The study was conducted at an academic secondary referral center in a prospective design. Patients were divided into two groups, and they were compared with healthy volunteers. The treatment group, including patients with GR, was given nasal saline wash four times daily and 100 µg of seleno-6 dietary supplements twice daily. The patient control group and the healthy volunteers were given only the nasal saline wash four times daily. Glutathione peroxidase, superoxide dismutase, and catalase levels were measured in all participants before and after treatment. In addition, the sino-nasal outcome test-20 and visual analog scale were applied before and after treatment. In the selenium supplement group, the visual analog scale, sino-nasal outcome test-20 scores, and enzyme levels were significantly improved compared with the untreated group. No adverse effects occurred in the selenium supplement group during the study. Supplemental selenium might be effective in the treatment of GR in terms of aging physiology and the oxidative system. However, large-scale randomized studies are needed to determine the optimal treatment.

How to cite this article:
Yalcinkaya E, Yazici H, Kayir H, Soy FK, Negm H. Selenium supplement for treatment of geriatric rhinitis.Egypt J Otolaryngol 2019;35:135-139

How to cite this URL:
Yalcinkaya E, Yazici H, Kayir H, Soy FK, Negm H. Selenium supplement for treatment of geriatric rhinitis. Egypt J Otolaryngol [serial online] 2019 [cited 2020 Feb 25 ];35:135-139
Available from:;year=2019;volume=35;issue=2;spage=135;epage=139;aulast=Yalcinkaya;type=0