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  Indian J Med Microbiol
 

Figure 1: Factor XIII A-subunit structure and locations of common coding polymorphisms. The structure shown is that of the recombinant factor A-subunit dimer, modeled using X-ray crystallography coordinates from Weiss

Figure 1: Factor XIII A-subunit structure and locations of common coding polymorphisms. The structure shown is that of the recombinant factor A-subunit dimer, modeled using X-ray crystallography coordinates from Weiss <iet al.</i 3. The catalytic core region is colored orange; the β sandwich, yellow; the 2β barrels, green; and the activation peptide, cyan. Highlighted are the active-site cysteine residue and five residues (Val34, Tyr204, Pro564, Val650, and Glu651) that show common variation in the general population 2.